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The Vaccine Thread

Cooked Crack

By Cooked Crack
in The Tailgate

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Cooked Crack

Cooked Crack

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21 minutes ago, Llevron said:

 

Ima tell prego wifey this. She got shingles the first year we moved in together and I thought she was going to die she was in so much pain. And shes the type to basically be able to lose a toe without blinking. Knowing that shingles can be way worse my calm her soul a bit. 

Going to guess your wife is under 50. She'll need a prescription or have to do it at her doctors.

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bearrock

bearrock

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12 minutes ago, Cooked Crack said:

Going to guess your wife is under 50. She'll need a prescription or have to do it at her doctors.

I think he meant that hopefully her anxiety over the impending labor pains will ease as she has already gone through something many felt were worse.

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Spaceman Spiff

Spaceman Spiff

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https://www.nationalgeographic.com/science/article/is-a-universal-coronavirus-vaccine-on-the-horizon

Quote

Every time a new variant comes along, COVID-19 vaccine and drug makers reassess their “recipes” to see if they work against an evolving virus—like Omicron, which has spread quickly around the globe in little more than a month.

Since the start of the pandemic in December 2019, the SARS-CoV-2 coronavirus that causes COVID-19 has mutated multiple times, giving rise to different variants. Because most vaccines were designed to recognize the original SARS-CoV-2 spike protein, or at least parts of it, more mutated variants like Omicron are better at escaping protection offered by the vaccines, although they still prevent severe disease.

Last month, vaccine makers talked about tweaking the formula to have an Omicron-specific vaccine handy, if needed. “But Omicron won’t be the last variant,” says Stephen Zeichner, an infectious disease specialist at the University of Virginia Medical Center. “It’s pretty clear that the virus continues to evolve and going forward there is a need for a universal COVID-19 vaccine or even a universal coronavirus vaccine.”

Since 2020, in preparation for the next deadly coronavirus outbreak, which experts think is only a matter of time, some scientists started developing vaccines that protect against multiple coronaviruses. Many efforts currently focus on known sarbecoviruses, which include SARS-CoV-1 and SARS-CoV-2, and some SARS-like bat viruses that have the potential to jump from animals to humans.

Early tests in animal models are showing promising results. “The great thing about having such vaccines is that they could handle potentially new [SARS-CoV-2] variants as well as the next horrible spillover viruses that’ll come down the road,” says structural biologist Pamela Björkman at the California Institute of Technology, who is developing a universal vaccine for some SARS-like viruses.

 

 

Here's hoping this is legit.  

 

It's offset, of course, by the fact that there's a contingent of the population that would be too ****ing stupid to take it.

 

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No Excuses

No Excuses

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On 12/26/2021 at 5:09 PM, PeterMP said:

 

Is there actually any evidence that we had the ability to generate the tests at the necessary volume and if we did, it would have made much of a difference?

 

The Vanity Fair piece is just odd to me.  The interpretation of a "vaccine only" response (from the Vanity Fair article) can be widely interpreted.  But even they say the Biden administration has put billions of dollars into ramping up test production.  $23 billion dollars doesn't seem like saying we don't care about something.  They talk about Europe like it is a great model for at home testing, but in Europe there have been issues with omicron.  If home testing is some great panacea, then why didn't the UK keep it in check?

 

It isn't like the FDA hasn't approved tests.  In May, there were multiple FDA approved home tests.

 

https://cen.acs.org/analytical-chemistry/diagnostics/covid-home-test-kit-review/99/i20

 

It's widely accepted that diminishing FDA restrictions on testing actually resulted in some not very good tests being put on the market and probably hurt our response and that home testing wasn't likely to going to actually solve the problem.

 

e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577497/

 

(Which is consistent with what we've seen in Europe and them still having issues with omicron.)

 

 (People frequently like to criticize the FDA, but I've known a few people that work at the FDA and mostly they are good people that work hard.  And there is a long history of complaints about the FDA being underfunded and under resourced.  But by May, the FDA had approved a handful of home tests.  Are we really blaming a Dec. out break on lack of approval by the FDA that had been approved well before that?)

 

Generally, this seems to me to be likely a case where people like to complain about government when there really wasn't much different that the government could do.  Given the restrictions and resources the relevant government entities have.  I'd say 20/20 hindsight is perfect.  But this isn't even a case of that.  There's really nothing that I've seen that suggest that a different approach would have changes things much at all.  London is shutting down bars.  We could have rushed tests through the FDA process, probably had some poorer tests on the market, spent $200 billion on ramping up at home testing, and be in the same situation.  For what?

 

(What has worked pretty well is China style lockdowns.))

 

The FDA's approval process for rapid tests, and in general at-home diagnostics, is hardly explicable by any logical standards: https://www.propublica.org/article/this-scientist-created-a-rapid-test-just-weeks-into-the-pandemic-heres-why-you-still-cant-get-it

 

There is no reason our shelves aren't stocked with $2 rapid tests like in Europe except that we (a) didn't approve tests fast enough, (b) don't allow tests approved in Europe, and (c) didn't subsidize their production in between waves when companies were destroying their stockpiles and shutting down production.

 

Rapid at-home tests wouldn't have prevented waves, but they have helped people in countries where they are cheap navigate around COVID in a much more effective way. There was no proper messaging informing the public on the proper use of rapid tests and what their proper use-case are (they are very good at informing you when you are highly contagious, or asymptomatic and contagious if you are going to visit family or friends).

 

They would prevent the long testing lines we see for PCR tests. Most importantly, we would not have had empty shelves right at the time omicron was peaking. Countries with a more nimble approval process did not have this problem, which tells you all you need to know.

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China

China

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Navy discharges 1st active-duty sailors for vaccine refusal

 

he Navy said Wednesday that it has discharged 23 active-duty sailors for refusing the coronavirus vaccine, marking the first time it has thrown currently serving sailors out of the military over the mandatory shots.

 

The discharges came as the Navy released new COVID-19 guidance that requires all deployed sailors and air crew to be vaccinated, but relaxes some quarantine practices on ships based on recommendations from the Centers for Disease Control and Prevention.

 

Click on the link for the full article

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