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BBC: China pneumonia outbreak: COVID-19 Global Pandemic


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We have a long, scary fight ahead, and many will not survive to see a full, public vaccine rollout. Today, my wife and I are going to get tested because of cold symptoms following a visit from her family. It is scary. However, today is nonetheless a good day in the fight. Here are some reasons to feel optimistic:

 

https://www.statnews.com/2020/11/09/four-reasons-for-encouragement-based-on-pfizers-covid-19-vaccine-results/

 

To further explicate this great Pfizer news, one of the most important features of the vaccine is that it is based on mRNA rather than DNA. This article gives a thorough overview of the differences, but I will break down a few of the highlights:

 

https://horizon-magazine.eu/article/five-things-you-need-know-about-mrna-vaccines.html

 

1. mRNA vaccines are built on the concept of tricking the body into creating viral proteins using messenger RNA, rather than merely sending out antibodies based on a code that it is familiar with once it comes into contact with a virus. Think of it as getting a jump on the opposition.

 

2. mRNA vaccines have never been licensed, but mRNA tech has been used to fight cancer in the past. There are many unknowns; these human trials that are currently being conducted are enormously important for vaccine development going forward.

 

3. mRNA vaccines may be easier to develop and produce than traditional vaccines. In this way, the timeline we have been given for distributing the vaccine may be a little more pessimistic than what is possible, as there is no precedent for producing an mRNA vaccine to scale.

 

"And by getting the human body to produce the viral proteins itself, mRNA vaccines cut out some of the manufacturing process and should be easier and quicker to produce than traditional vaccines. ‘In this situation, the major benefit is that it's easy to produce (and) it will also probably be relatively easy to do an upscaling of production, which of course, is very important if you think about deployment throughout Europe and the world,’ said Prof. Bekeredjian-Ding."

 

A successful mRNA vaccine, or several, would be a turning point in vaccine production that could impact the way we treat any number of common illnesses. Science just needed the opportunity to break status quo.

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Biden was correct when he stated that even if approved a vaccine would take a while to roll out and distribute.  And with the Pfizer vaccine cold chain distribution issues would make it more difficult:

 

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Experts say it will be a “Herculean effort” requiring several new technologies to work in flawless concert to safely deliver every dose of the drug. Pfizer said it plans to ask the U.S. Food and Drug Administration for emergency use authorization next week, when it has the required two months of safety data.

 

The vaccine will be formulated, finished and placed in cold storage in the pharmaceutical giant's Kalamazoo, Michigan, facility, its largest such plant in the country. During the shipment and storage, the vaccines must be kept at 94 degrees below zero Fahrenheit in order to maintain optimal efficacy. Each package can contain 1,000 to 5,000 doses.

 

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7 hours ago, Larry said:

 

Certainly agree that a rumored vaccine is not an instant fix.  

 

Might make it easier to convince people to do a lockdown, though.  

 

I had this discusssion with my wife not so long ago.

 

Vaccine is good, but it depens on how long it last. (Which I'm pretty sure we have no clue right now).

 

Right now in France, due to a huge effort we're testing around 1.5 to 2M people a week. Since we're close to 70M, it would take around 7 Month to get everyone vaccined.

If the Vaccine is good for a year only, it's gonna be a perpetual cycle of vaccining the whole population...

 

Not really a good option either.

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NY state pulls liquor license of country club that hosted 'super spreader' wedding

 

Gov. Andrew Cuomo (D-N.Y.) announced on Monday that a Long Island country club’s liquor license was suspended after it hosted a “superspreader” wedding that has been linked to more than 30 cases of the coronavirus.

 

The New York State Liquor Authority charged the North Fork Country Club with multiple charges of failing to comply with the state’s COVID-19 restrictions. The venue is currently banned from serving alcohol until the violations are addressed.

 

As Bloomberg reports, 113 guests gathered on Oct. 17 at the club in violation of New York’s 50-person limit on non-essential events. Thirty-four people tested positive for COVID-19 after the event. 

 

Click on the link for the full article

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The world has surpassed 50 million confirmed coronavirus cases

 

There are over 50 million confirmed coronavirus cases worldwide, according to the latest data compiled by Johns Hopkins University. 

 

With about 10 million cases, the United States is the country with the most confirmed coronavirus cases, followed immediately by India and Brazil. At least 230,000 people have died from the disease in the United States.

 

The World Health Organization declared the coronavirus a pandemic on March 11.

 

The coronavirus has killed more Americans than every war US troops have died in since 1945 combined, Business Insider's John Haltiwanger reported. The leading cause of death for Americans, heart disease, typically kills fewer than 650,000 people a year in the US.

 

Click on the link for the full article

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3 hours ago, Wildbunny said:

 

If the Vaccine is good for a year only, it's gonna be a perpetual cycle of vaccining the whole population...

 

Not really a good option either.

You mean like the flu vaccine...the pneumonia vaccine....etc...

2 hours ago, China said:

NY state pulls liquor license of country club that hosted 'super spreader' wedding

 

Gov. Andrew Cuomo (D-N.Y.) announced on Monday that a Long Island country club’s liquor license was suspended after it hosted a “superspreader” wedding that has been linked to more than 30 cases of the coronavirus.

 

The New York State Liquor Authority charged the North Fork Country Club with multiple charges of failing to comply with the state’s COVID-19 restrictions. The venue is currently banned from serving alcohol until the violations are addressed.

 

As Bloomberg reports, 113 guests gathered on Oct. 17 at the club in violation of New York’s 50-person limit on non-essential events. Thirty-four people tested positive for COVID-19 after the event. 

 

Click on the link for the full article

Cuomo isn't ****ing around. He's been revoking liquor licenses left and right in this state...all over the state.

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20% of recovering  #COVID19 patients develop mental illness within 90 days, says large US study.  Increased *first-time diagnosis* of anxiety, depression & insomnia by 2-fold! And researchers also found significantly higher risks of dementia. 

 

So for Trump no change.  

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6 hours ago, Xameil said:

You mean like the flu vaccine...the pneumonia vaccine....etc...

Nobody's doing it for the full population all the time. It's mostly targeted, and not always mandatory in many cases. (Also, we ordered 15M doses pf Flu vaccine this year in France, which is roughly 25% of the whole population. Definately not the same kind of of what we're gonna want to do with Covid here).

Be reminded as well that some got infected in March/April are getting infected now. If immunity is less than a year, it's even worse.

 

Now if it takes 7 months to vaccine everyone. It means that for November 2021, you have to start in February 21. While the flu, you start doing it in what? October?

Also, flu vaccine isn't always 100% right, sometimes, it just doesn't work, because it's based on last year's flu.

 

Gotta need trillions, if not more of hen and eggs...

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12 hours ago, Wildbunny said:

I had this discusssion with my wife not so long ago.

 

Vaccine is good, but it depens on how long it last. (Which I'm pretty sure we have no clue right now).

 

Right now in France, due to a huge effort we're testing around 1.5 to 2M people a week. Since we're close to 70M, it would take around 7 Month to get everyone vaccined.

If the Vaccine is good for a year only, it's gonna be a perpetual cycle of vaccining the whole population...

 

Not really a good option either.

 

Well you don't need to vaccinate 100% of the population every year. The numbers that have been floating around for Covid-19 herd immunity are between 60-70%. Also, for life to turn back to somewhat normal you focus on old people, people with pre-conditions, health care workers, etc. first. Even though young people can also get seriously sick, the main issue with Covid is the overload of the health care system, and that is primarily caused by old people and people with pre-conditions getting sick.

If that vaccine is effective for one year, that would be great news, and it seems that is the case - remember the research won't stop here.

From a FT artcle about the BioNTech vaccine: "[The founder] expects the vaccine’s immune response to last for “at least one year”, adding that the vaccine-induced antibodies were shown to block about 20 different mutations of Sars-Cov-2. “There's a very low likelihood that a [mutation of] the virus can overcome the immune response,” he predicted.

 

Also testing and vaccinating are very different things. One issue with tests, besides limited reagents, is that labs have a finite capacity because the tests need to be evaluated, interpreted and administered. If you have a working vaccine you just need two shots within a month and that's it. That takes about 2-3 minutes and you don't need to do anything afterwards. So the main issue here is the availability of enough doses of the vaccines. However, if that vaccine is proven effective and can be scaled up as easy as Pfizer suggests (they say that they can deliver up to 1.3 bn doses in 2021) you could easily vaccinate the whole population of your country within weeks.

 

So while obviously not everything is ideal, it's definitely better than we could have expected. A 90% effectiveness and the assumption that the vaccine is effective for about a year with some resilience against mutations is about as good as it gets within not even a year in the development and testing process.
 

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