Nah, the problem with Knight Rider is that too many of us own KITT these days. Our cars have computers in them. We have cruise control, GPS, it can tell us where the best place to go is. Sure, we look turbo boost and armour, but the wonder of KITT is gone.
With Start Trek, we do have communicators. Hell our smart phones are better than what Kirk used. We've even developed tricorders. The magic of exploration and alien encounters though... that's still there. Laser battles (or phasers if you must) and Warp drives still tickle the imagination. Sure, we've sent an unmanned probe beyond the solar system, but that adds to it... there's a lot of possibility still out there if you get smart writers.