Sticksboi05

I would tell her there is firm scientific evidence not a single variant exists that can evade the mRNA vaccines - less efficacious yes but still will prevent worst outcomes. The scariant headlines have been miserable, generally misinformed, and fear-mongering. Double mutant is silly. There are actually 17 mutations on the UK variant, none of which stop the vaccines from doing their job.

At this point, states need to move from appointments to walk-ins. We're at the point where simple convenience will get a lot more people to get vaccinated. Already had two friends up here in NYC say this makes it a lot easier for them vs. having to book.

Everyone is different - my friend said he felt like he got hit by a truck after Pfizer 2. I got Moderna and had nothing after second dose - no fever, nausea, sweats. A couple of leg chills at best. Grab a pedialyte beforehand and you'll be good to go.

Folks, we're reaching a critical point in the vaccination campaign where we're running out of people who are excited to get one. If you know of any friends or family who are 50/50 and have specific questions, please start dropping them in here. We can reply with insights/data from experts who aren't being put on the local news at 6 or given as much of a platform as Fauci. Every little bit helps. I am NOT trying to go back to last March/April ever again.

They are but it's still extremely rare. Hopefully once this is put out, it's put out for good. Cannot deal with last March and April again.

It should be noted though that is just a guess from Pfizer, there are medical experts who also think protection could last years given the fact that natural immunity to SARS-Cov-1 was 2.5-3 years. Question is do more variants change the game, or have we seen most of what this virus can do to mutate. It doesn't have unlimited options but there could be more.

What does that have to do with the delays in messaging that have continued under the Biden administration? Also I don't think Trump would stop the CDC from messaging things positive on the vaccines that would give his ego maniacal ass more credit for Warp Speed.

I disagree, I think they had a duty to be fully transparent no matter how rare, and to ensure there is protocol for future cases no matter how rare they are. It's more about ensuring medical practitioners know what to do if their patients present with such symptoms. Public health agencies like the CDC slow to update their recommendations and messaging. Media has been out in front on new research and suggesting we change behaviors.

1. FB Marketplace is absolutely the GOAT 2. I definitely will not be breaking the bank on my purchase!

My apartment came with a propane grill. No thanks, ordering me a new charcoal bad boy, chimney and getting grill season underway. I was always a "well for big parties use the propane" guy but hosted my company last summer with my old charcoal grill with ease, and the flavor profile is superior.

I think the fact that they were willing to pause JNJ after 6 cases identified in 7 million doses is a good, telling sign. They are not going to take anything lightly. What would be unacceptable is if they saw this frequently in the trials and still said let's go for it without transparency. I think the vaccine messaging from public health officials has been trash as far as convincing hesitant people to take it. And Fauci is leading the charge. It's more "safe and effective" generalities vs. giving people the full data. Essentially they feel the best way is to treat people like they're too dumb to get anything without a medical background. More information is good - tell people the risks, all of them, and explain how low the prevalence is. Explain why it may be, how you address it and why pausing makes everyone safer because even if you DO happen to suffer a rare side effect, you know what to keep watch for and treatments are ready.

Looking back after this I think we're going to see a harsh reality that public health guidance is way too slow to react to new data and research. People are still obsessively saniziting surfaces despite clear, presented evidence last SUMMER the risk was extremely low, we still have people walking around on empty / not that crowded streets wearing masks when that is pretty clearly not necessary, and yet we allow people to go into restaurants and unmask before the food arrives. The mandates don't fit how the virus actually spreads. Then we still have mass amounts of people on the "we don't know if the vaccine curbs transmission" train when that is old news now and we know it does. Just way to slow to update the file from the CDC and others throughout this entire thing.

There is literally zero truth to that myth. That's like telling people you can only have a cold if you have a severe fever.

Technically I have my two weeks but I already feel the microchip working.

Fully vaccinated as of today. BUY MICROSOFT!!!!

We're at 40% of the population, it's very possible once we hit 50% you'll start seeing declining numbers at least in some regions. The UK's numbers are dropping because they are holding back second doses to get more of a wall up in general. Many public health experts here think that was the right call, others disagree.

I'm on your side - I've already had to explain to many friends that they have a better chance of being struck by lightning.

I think there is an issue with public health messaging when they say "it's safe and effective". We constantly try to simplify things for people as if that is the right way to go, and it ALWAYS backfires. If someone hears a million times, safe and effective, they want to know ... HOW safe and HOW effective. Safe when it comes to any sort of therapeutic or medicine, even natural supplements, will never mean there is a 0.0% chance of a bad reaction in someone. Biology is full of exceptions and people need to understand a medicine can be exceedingly safe and that doesn't mean there is literally no risk. And now despite the explanations of what the efficacy numbers mean we have people like "wait, the vaccine doesn't mean I can't get it, what's the point". This has to be a big takeaway after the pandemic, how do we fix these things.

On Mantha - he is a better player than Vrana and may more versatile. Jake has no physical presence, does not play any defense and is speed or nothing. Now that speed is a massive asset and he could develop into a 30-goal scorer given a new role on a new team with proper PP time, but for Lavi's system it doesn't work. If Mantha is motivated he can do much more all over the ice. The 1st rounder hurts but player for player we win and Panik is addition by subtraction because he was overpaid and it was going to be worse now that the cap will not go up for probably two years. We get a very good, borderline 1st line player under team control for three years. Vrana was due a huge pay day at season's end, and would have cost too much. Better to get something for him than nothing.

Yup - the research was sparked in 1971 by the frog/rabbit mRNA transfer experiment in the UK. The first animal trial for an mRNA vaccine was in 1993 (mice), which successfully produced T-cell responses against the flu, and then eventually antibody responses against the flu and the RSV respiratory virus.

I prefer an osteopath for such issues.

Another failure of the media is making people think researchers just came up with mRNA technology in 2020. In fact, research into mRNA for therapeutics has been going on for 50 years since UK researchers put rabbit mRNA into frog cells and saw the cells make protein that a rabbit would. The first RNA drug was approved in the late 1990s and the first mRNA vaccine trial was done in 2008, most failures before, because of lack of efficacy as mRNA doesn't last very long in the body (thanks to ribonucleases).

I think there's a few things here: 1. I want everyone to get vaccinated who falls under the EUA guidelines but I will never ostracize people for being hesitant or wanting as much information as possible. When Trump was considering going around the FDA to approve them last fall, there would have been ZERO shot I even consider taking it and even Fauci said he would have told people don't take it. Attacking people who simply want as much info. as possible is counterproductive. It's like trying to pull people put of QAnon by yelling at them. 2. Comparing the virus and this issue with the CVT – as of now the odds of clotting when you get COVID-19 are as high as 7-11%. Even in mild cases people clot in the lungs, and that is a big misconception right now - that if you don't go to the hospital the virus did no damage. Lots of mild cases have caused long-term issues and who knows what that means down the line (the same question people ask about vaccines). Compare that 7-11% in newer studies to the 1 in a million odds of CVT from JnJ vaccine and it's not really a close comparison. Of course as they research the potential link, we should absolutely amend who gets what vaccine to lower the risk even more. That all of the cases are women 18-48 is not a coincidence potentially. 3. 90% of adverse reactions to vaccines are within the first 40-45 days, which is why the FDA asked to see at least 60 days of safety data. If this risk ends up being the 1 in a million it is now, that's hard to see even if you did a clinical trial of 500,000 people over 10 years, you may not see it in a single one of them. The odds of the same clot is much higher in women who take birth control pills (1 in 3000). You have a better chance of being struck by lightning. OTC NSAIDS like Advil put people in the hospital every year - thousands. Nobody wanted to read today's headlines but the good thing is, the observation system is working, they are going to do the proper analysis to see what's happening and they didn't try to cover it up. It will hurt in the short run as people get nervous, but the transparency is better than if they said ehh 1 in a million is so low why address it and scare people. It could be there is something to the adenovirus vector vaccines (JNJ/AZ) but regardless we put things into our bodies everyday that probably have way higher odds of long-term effects - soda, white bread, trans fats, highly processed foods etc.

Got Moderna No. 1 yesterday. So far just a sore arm, mostly shoulder. I'm hearing people delaying because they don't want Janssenn vaccine. If you know people who could get it, tell them to. The efficacy numbers are not equivalent and the analysis doesn't get into antibody vs. T-cell response. It's very possible that there are some benefits to JNJ even over the mRNA vaccines.

https://twitter.com/SteveKopack/status/1366895728694611973 The data on protection + early data on significant transmission reduction is clear. We're on our way to summer being normal.