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BBC: China pneumonia outbreak: COVID-19 Global Pandemic


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I've been talking with my mom (retired RN) a lot more than usual lately. She's not doing her normal R thing. She's very worried, she knows this is real, the death count is on the low end & it's gonna get worse without a vaccine. (And let's not forget, most vaccines take a decade or more...we're really being optimistic with a 12-18 month estimate.)

We both hate not being on the move, and we both hate cooking just for ourselves...but we strongly agree that patience (neither of us have that, either 🤣) is what's necessary. 

 

Take a good, deep breath. It helps. 

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A lot of people don't realize how dangerous this virus is yet, it is NOT just a respiratory virus. It may start as one, but then it becomes a cardiovascular virus via it's direct attack of the endothelial cells that line the blood vessels throughout our body. This **** scares the **** out of me, because I already have stage 3 chronic kidney disease from a berger's immune inflammation response and this virus can end up doing the same type of damage. My boss has already tested positive for COVID and I'm just counting down the days to see if my contact with him from the week before last was enough to get me infected.

 

Plus, I have seizures from severe spinal stenosis and the last thing I need is anything else ****ing with my brain and central nervous system. I just regained my sense of smell on the left side of my face from months of work and I not gonna lose that progress to this virus.

 

Quote

But many scientists have come to believe that much of the disease’s devastation comes from two intertwined causes.

The first is the harm the virus wreaks on blood vessels, leading to clots that can range from microscopic to sizable. Patients have suffered strokes and pulmonary emboli as clots break loose and travel to the brain and lungs. A study in the Lancet, a British medical journal, showed this may be because the virus directly targets the endothelial cells that line blood vessels.

 

 

The second is an exaggerated response from the body’s own immune system, a storm of killer “cytokines” that attack the body’s own cells along with the virus as it seeks to defend the body from an invader.

 

Research and therapies are focused on these phenomena. Blood thinners are being more widely used in some hospitals. A review of records for 2,733 patients, published Wednesday in the Journal of the American College of Cardiology, indicates they may help the most seriously ill.

 

“Things change in science all the time. Theories are made and thrown out. Hypotheses are tweaked. It doesn’t mean we don’t know what we are doing. It means we are learning,” said Deepak Bhatt, executive director of interventional cardiology at Brigham and Women’s Hospital in Boston.

 

Inflammation of those endothelial cells lining blood vessels may help explain why the virus harms so many parts of the body, said Mandeep Mehra, a professor of medicine at Harvard Medical School and one of the authors of the Lancet study on how covid-19 attacks blood vessels.

That means defeating covid-19 will require more than antiviral therapy, he said.

 

“What this virus does is it starts as a viral infection and becomes a more global disturbance to the immune system and blood vessels — and what kills is exactly that,” Mehra said. “Our hypothesis is that covid-19 begins as a respiratory virus and kills as a cardiovascular virus.”

 

The thinking of kidney specialists has evolved along similar lines. Initially, they attributed widespread and severe kidney disease to the damage caused by ventilators and certain medications given to intensive-care patients, said Daniel Batlle, a professor of medicine at Northwestern University Feinberg School of Medicine.

 

Edited by Fresh8686
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54 minutes ago, Fresh8686 said:
Edit
 

A lot of people don't realize how dangerous this virus is yet, it is NOT just a respiratory virus. It may start as one, but then it becomes a cardiovascular virus via it's direct attack of the endothelial cells that line the blood vessels throughout our body. This **** scares the **** out of me, because I already have stage 3 chronic kidney disease from a berger's immune inflammation response and this virus can end up doing the same type of damage. My boss has already tested positive for COVID and I'm just counting down the days to see if my contact with him from the week before last was enough to get me infected.

 

Plus, I have seizures from severe spinal stenosis and the last thing I need is anything else ****ing with my brain and central nervous system. I just regained my sense of smell on the left side of my face from months of work and I not gonna lose that progress to this virus.

 

 

 

My very best wishes and hopes for your health. All of us without any major health concerns take that for granted sometimes. And that is why many others just don't understand the risk they are putting others at is just as important as their own risk. By ignoring the precautions they are putting other people lives at risk without their knowledge or consent. 

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Thanks y'all I appreciate it. We are all in this together and it's important we keep that feeling of connection alive and realize we need to share in our care and responsibility for each other. There are so many others like me and many more who are in even worse situations and it breaks my soul to think of the agony and fear they're dealing with. Then I think about the people who take their health for granted, blindly kicking down the sandcastles of frail health these others are trying to protect and I am filled with so much rage. 

 

I've worked so ****ing hard trying to climb out of the hell my body has become only to find a new hell to deal with in the threat of this virus. But, at the same time I feel blessed, because there are people dealing with both hells and many other different flavors as well, who don't have the shelter and support I do. 

 

I can't wait to be healthy enough to help those people and to make sure no one ever again feels the types of things I've had to feel.

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Lowest death rate in two weeks for va... we should be reopening soon hopefully...🤗

 

https://www.wavy.com/news/health/coronavirus/virginia-may-11-covid-19-update-va-passes-25k-cases-lowest-daily-increase-in-deaths-11-in-two-weeks/


lookin forward to going to Busch Gardens... Probably at least 6 weeks before that happens... 😕

 

other than that I will probably stay home anyway... 

 

Edited by CousinsCowgirl84
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12 minutes ago, The Evil Genius said:

 

Karens, bro. 😁

 

Ps. I kid. I just think anyone who is wishing major germ factories to reopen righr now are being a tad entitled. 

And a lot stupid. There's no other word. "Ignorant" ain't gonna fly on this one, especially for one who thinks they're smarter than everyone else who is reading (if they are) what visionary posts. 

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43 minutes ago, TryTheBeal! said:

Amusement parks hardly seem like a priority.

 

On the other hand, if they limit capacity to say 15%...That might be fun.  Get in, no lines, hit the coasters, smash a funnel cake and bounce.  Knock it out in like 2 hours.

Maybe enough people will stay home.... on the other hand I went to the botanical gardens two weeks ago and it was packed, which I was surprised by...

 

 

I don’t think theme parks are a priority necessarily but they seem less risk than a casino, restaurant, gym, of movie theatre...

 

something to look forward to anyway. It’s going to be a lot longer before I’d trust the other places. 

Edited by CousinsCowgirl84
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43 minutes ago, TryTheBeal! said:

Amusement parks hardly seem like a priority.

 

On the other hand, if they limit capacity to say 15%...That might be fun.  Get in, no lines, hit the coasters, smash a funnel cake and bounce.  Knock it out in like 2 hours.

 

I've been trying to go to Busch Gardens the past two years. Id need more than a couple hours in just the beer gardens. I knew I shoulda gone last year when theys giving out free beer. 😔

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2 hours ago, CousinsCowgirl84 said:

Lowest death rate in two weeks for va... we should be reopening soon hopefully...🤗

 

https://www.wavy.com/news/health/coronavirus/virginia-may-11-covid-19-update-va-passes-25k-cases-lowest-daily-increase-in-deaths-11-in-two-weeks/


lookin forward to going to Busch Gardens... Probably at least 6 weeks before that happens... 😕

 

other than that I will probably stay home anyway... 

 

 

We aren't testing enough to be taking victory laps and the there's dips in reporting every weekend, likely from folks being off and waiting for Monday to start making the count accurate again.

 

History repeating itself, folks clamored to open up early during Spanish Flu and it lead to a worse second spike.  This is a dead cat bounce with dead bodies instead.

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8 minutes ago, Renegade7 said:

 

We aren't testing enough to be taking victory laps and the there's dips in reporting every weekend, likely from folks being off and waiting for Monday to start making the count accurate again.

 

History repeating itself, folks clamored to open up early during Spanish Flu and it lead to a worse second spike.  This is a dead cat bounce with dead bodies instead.


Im not sure if we get that big spike for a second wave. There’s a huge difference in how messaging and news travels today and people are unlikely to resume normal activity even if the first wave wanes.
 

I think we are going to see a very prolonged first wave that never really goes down but maybe doesn’t see huge upticks either. People won’t have the confidence to go to restaurants etc, offices won’t resume normal activity and meetings/coworking will happen over computers. We’ll see spikes in cases in the usual places: meat packing plants, prisons, nursing homes, etc where social distancing is impossible. 
 

This country is basically lining up to sacrifice old people in nursing homes, prisoners and anyone who works in an essential, densely packed environment. 

Edited by No Excuses
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@No Excuses can see a situation where like you said the first wave doesn't actually stop and we stop calling it that when flu season starts. 

 

Whether by November we are calling it the second spike or continuation of first wave might be ambiguous at best by then.

 

It's frustrating watching claims we winning the game so far by counting first downs in the first quarter.

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1 hour ago, AlvinWaltonIsMyBoy said:

I had to go to Cummings, Georgia today. You would swear there was no outbreak around there.

 

Gonna be a long haul, me thinks. Let’s hope nature weakens it at least and it goes easy on us.

 

I live in Atlanta and play golf on the weekends. There are very specific Coronavirus rules And I noticed the same thing you did. In many places, especially jsut outside the city, it looked like there were no restrictions at all. 
 

I also saw where some 70,000 people from other states not on lock-down came here, maybe more. 

 

We will see if this leads to a spike in cases. I hope not, but it's hard to beat science and mother nature. 

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Those of you who think that the spikes won't happen or will be milder need to read and comprehend the following.

 

My daughter's doctor, Dr. Christine Mann who happens to be running for Congress in my district, spoke with her recently and she predicts a spike in the Summer and the Fall due to relaxing safeguards. 

 

It's up to us to take care of ourselves because some governments don't give a ****.

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